Estrogen receptor
Progesterone receptor
ERR

Progesterone receptor 選擇性抑制劑 | 激動劑 | 拮抗劑 | 化學產(chǎn)品 | 調(diào)節(jié)劑

目錄號	產(chǎn)品名	產(chǎn)品描述	Selective / Pan	IC50 / Ki
S2606	Mifepristone	Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.	Selective	Progesterone receptor, IC50: 0.2 nM
S3167	Altrenogest	Altrenogest (A35957, RU2267,R2267) is a progestogen structurally related to veterinary steroid trenbolone.	Selective
S2611	Ethisterone	Ethisterone(17α-Ethynyltestosterone) is a progestogen hormone being considered to treat prostate cancer.	Selective
S1727	Levonorgestrel	Levonorgestrel (D-Norgestrel) is a female hormone that prevents ovulation.	Selective
S1377	Drospirenone	Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.	Selective
S4097	Dydrogesterone	Dydrogesterone (NSC 92336) is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.	Selective
S1914	Pregnenolone	Pregnenolone(3β-Hydroxy-5-pregnen-20-one) is an endogenous steroid hormone, used in the treatment of fatigue, Alzheimer’s disease, trauma and injuries.	Selective
S3081	Ulipristal Acetate (CDB 2914)	Ulipristal acetate (CDB-2914, HRP 2000, RU 44675) is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.	Selective
S2567	MPA (Medroxyprogesterone acetate)	MPA (Medroxyprogesterone acetate) is a synthetic progestin and act as a potent progesterone receptor agonist, used to treat abnormal menstruation or irregular vaginal bleeding.	Selective
S3160	Ethynodiol diacetate	Ethynodiol diacetate (8080 CB,Ethynodiol acetate) is one of the first synthetic progestogens used in contraceptive pills.	Selective
s1251	Dienogest	Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.	Selective
S1705	Progesterone	Progesterone is an endogenous steroid hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. A potent agonist of the nuclear progesterone receptor (nPR) with Kd of 1 nM; An agonist of the membrane progesterone receptors(mPRs); An antagonist of the σ1 receptor.	Selective
S1304	Megestrol Acetate	Megestrol acetate (BDH1298, SC10363) is a synthetic progestogen, used to treat breast cancer and loss of appetite.	Selective